Surface-enhanced Raman spectroscopic analysis of uric acid.
- Author:
Shangyuan FENG
1
;
Duo LIN
;
Yongzeng LI
;
Zufang HUANG
;
Yan'an WU
;
Yue WANG
;
Juqiang LIN
;
Rong CHEN
Author Information
1. Key Laboratory of OptoElectronic Science and Technology for Medicine, Ministry of Education, Fujian Normal University, Fuzhou 350007, China.
- Publication Type:Journal Article
- MeSH:
Metal Nanoparticles;
chemistry;
Silver;
chemistry;
Spectrum Analysis, Raman;
methods;
Surface Properties;
Uric Acid;
analysis
- From:
Journal of Biomedical Engineering
2012;29(3):541-545
- CountryChina
- Language:Chinese
-
Abstract:
Based on Ag nanoparticles as the surface-enhanced Raman spectroscopy (SERS)-active nanostructure, the SERS of uric acid was presented in the paper. The absorption spectroscopies of uric acid and the mixture of silver colloids and uric acid were measured. The possible enhancing mechanism of the uric acid on silver colloid was speculated. The characteristic SERS bands of uric acid were tentatively assigned. The influence of absorption time and different ion on the SERS of uric acid were also discussed. The SERS spectral intensity changes linearly with the uric acid concentration, which indicated that the SERS might provide a new kind of direct and fast detecting method for the detection of uric acid. The detection limit of uric acid in silver sol is found to be 1 mg/L.
