The sub-microsecond pulser applied for electroporation effect.
- Author:
Yafang TAN
1
;
Hongchun YANG
;
Jianxing WU
;
Xiaolin YANG
;
Yi ZHANG
;
Gang ZENG
;
Xiaoyu ZHANG
Author Information
1. Physical Electronics College, University of Electronics Science and Technology of China, Chengdu 610054, China.
- Publication Type:Journal Article
- MeSH:
Animals;
Cell Line, Tumor;
Cell Membrane;
Electricity;
Electroporation;
instrumentation;
methods;
Equipment Design;
Microtechnology;
instrumentation;
Neoplasms;
ultrastructure
- From:
Journal of Biomedical Engineering
2012;29(4):615-619
- CountryChina
- Language:Chinese
-
Abstract:
A sub-microsecond pulse generation applied for electroporation effects of tumor cell is presented in this paper. The principle of the generator is that the expected pulse waveform is intercepted from the RC discharge curve by controlling the on-off states of two IGBT modules with a synchronous controller. Experimental tests indicate that the generator can produce adjustable pulse waveform parameters with 0.5-3.5kV amplitude, 300-800 ns pulse duration, 1-400Hz repetition frequency rate, and it is suitable for the study of the electroporation effect experiments.
