Mechanisms responsible for antitumor activity of melanoma differentiation-associated gene -7/interleukin-24.
- Author:
Min YANG
1
;
Wen-Bin QIAN
Author Information
1. The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310003, China.
- Publication Type:Journal Article
- MeSH:
Apoptosis;
Cell Proliferation;
Genetic Therapy;
methods;
Humans;
Interleukins;
biosynthesis;
genetics;
Neoplasms;
metabolism;
pathology;
therapy;
Tumor Suppressor Proteins;
biosynthesis;
genetics
- From:
Journal of Zhejiang University. Medical sciences
2007;36(1):98-102
- CountryChina
- Language:Chinese
-
Abstract:
The melanoma differentiation-associated gene-7/interleukin-24 (MDA-7/IL-24) is a novel candidate of tumor suppressor, which can experimentally inhibit the proliferation of cancer cells and induce apoptosis of various human malignant cells.