Polymorphism of five X-STR loci in Chinese Achang ethnic group.
- Author:
Shan-Zhi GU
1
;
Jing-Fang ZHONG
;
Zhi-Qiang MU
;
Sheng-Bin LI
Author Information
- Publication Type:Journal Article
- MeSH: Alleles; China; Chromosomes, Human, X; genetics; Female; Gene Frequency; Genotype; Humans; Male; Microsatellite Repeats; genetics; Polymorphism, Genetic
- From: Journal of Zhejiang University. Medical sciences 2007;36(2):185-190
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo investigate the genetic polymorphism and applied value in forensic medicine of five short tandem repeats (STRs) loci(DXS7130, DXS7132, DXS7133, DXS6804 and DXS8378) on X-chromosome in Achang ethnic group.
METHODSAllele frequency and genotype distribution of five X-STR loci among 100 unrelated individuals from Achang ethnic group were analyzed by PCR following polyacrylamide gel electrophoresis and silver staining. Hardy-Weinberg equilibrium of females was tested and forensic parameters were calculated.
RESULTAll the five STR loci were polymorphic in Achang ethnic group. Chi-square test indicated that genotype distribution of females was in accordance with Hardy-Weinberg equilibrium.
CONCLUSIONThese results enrich Chinese genetic database and can be applied to individual identification, paternity testing and population genetics.
