Relationship between androgen levels and pathological changes of coronary atherosclerosis in elderly males.
- Author:
Hai-feng GU
1
;
Yun-mei YANG
;
Zhe-rong XU
Author Information
- Publication Type:Journal Article
- MeSH: Aged; Coronary Artery Disease; blood; pathology; Enzyme-Linked Immunosorbent Assay; Humans; Male; Middle Aged; Risk Factors; Sex Hormone-Binding Globulin; metabolism; Testosterone; blood
- From: Journal of Zhejiang University. Medical sciences 2007;36(4):382-385
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo explore the relationship between androgen levels and pathological changes of coronary artery in elderly males.
METHODSOne hundred and twenty-eight in-patients who received coronary angiography were divided into four groups: single vessel lesion group (SV group), double vessel lesion group (DV group), three vessel lesion group (TV group) and control group. The levels of serum total testosterone (TT) and sex hormone binding globulin (SHBG) were assayed by ELISA, and free testosterone (FT) calculated with the Vermeulen formula.
RESULTSThere was significant difference in FT levels among these four groups, while there was no statistical difference in TT levels. FT level in TV group was lower than that in DV group and SV group.
CONCLUSIONSerum levels of free testosterone may be correlated with pathological degree of coronary artery.
