The induction of CYP3A regulated by pregnane X receptor and its significance in drug metabolism.
- Author:
Yu-Guang WANG
1
;
Sheng-Qi WANG
;
Yue GAO
Author Information
1. Institute of Radiation Medicine, Academy of Military Medical Sciences, Beijing 100850, China.
- Publication Type:Journal Article
- MeSH:
Animals;
Bridged Bicyclo Compounds;
metabolism;
Cytochrome P-450 CYP3A;
biosynthesis;
genetics;
Drug Design;
Drug Interactions;
Enzyme Induction;
Humans;
Lithocholic Acid;
metabolism;
Phloroglucinol;
analogs & derivatives;
metabolism;
Receptors, Cytoplasmic and Nuclear;
genetics;
metabolism;
physiology;
Receptors, Steroid;
genetics;
physiology;
Signal Transduction;
Terpenes;
metabolism;
Transcription Factors;
genetics;
metabolism
- From:
Acta Pharmaceutica Sinica
2006;41(1):1-6
- CountryChina
- Language:Chinese
