Isolation and structure identification of chemical constituents from Patrinia villosa.

Author: Jin-yong PENG ¹ ; Guo-rong FAN ; Yu-tian WU
Author Information

1. Shanghai Key Laboratory for Pharmaceutical Metabolite Research, School of Pharmacy, Second Military Medical University, China.
Publication Type:Journal Article
MeSH: Apigenin; chemistry; isolation & purification; Flavanones; chemistry; isolation & purification; Isoflavones; chemistry; isolation & purification; Luteolin; chemistry; isolation & purification; Molecular Conformation; Molecular Structure; Patrinia; chemistry; Plants, Medicinal; chemistry; Quercetin; chemistry; isolation & purification
From: Acta Pharmaceutica Sinica 2006;41(3):236-240
CountryChina
Language:Chinese
Abstract:
AIMTo study the chemical constituents of Patrinia villosa Juss.
METHODSSolvent extraction, silica gel column and preparative liquid chromatography were used to separate the chemical constituents, and the chemical structures were elucidated by physico-chemical properties and spectra data.
RESULTSEight compounds were isolated and identified as bolusanthol B (1), (2S)-5, 7, 2', 6'-tetrahydroxy-6,8-di (gamma,gamma-dimethylallyl) flavanone (2), orotinin (3), (2S)-5, 7, 2', 6'-tetrahydroxy-6-lavandulylated flavanone (4), 3'-prenyl-apigenine (5), luteolin (6), quercetin (7) and apigenin (8).
CONCLUSIONCompound 2 and 4 are new compounds, compounds 1, 3 and 5 were separated from Patrinia genius for the first time, compounds 6, 7 and 8 were isolated from Patrinia vollosa Juss for the first time.