Application of highly accurate nephelometric titration in the assaying of phenytoin sodium.
- Author:
Tao YI
1
;
Xian-cheng ZHAN
;
Cheng-rong LI
;
Ning HE
Author Information
- Publication Type:Journal Article
- MeSH: Nephelometry and Turbidimetry; methods; Phenytoin; analysis; Reproducibility of Results; Solutions; Titrimetry; methods
- From: Acta Pharmaceutica Sinica 2006;41(4):370-375
- CountryChina
- Language:English
-
Abstract:
AIMTo determine phenytoin sodium by a highly accurate nephelometric titration.
METHODSThe titration operating conditions were optimized and the solubility product constant of phenytoin silver precipitation was determined.
RESULTSThe result of the titration is comparable to those of control experiments.
CONCLUSIONThe proposed method has been found to be accurate, precise, specific, reproducible, and linear.
