Effect of propranolol gel on infantile hemangiomas.
- Author:
Ya-Nan ZHAI
1
;
Hong-Tao SONG
;
Shao-Quan CHEN
;
Min-Xin ZHANG
;
Cheng-Jin LI
;
Yin XIA
;
Lie WANG
Author Information
- Publication Type:Journal Article
- MeSH: Female; Hemangioma, Capillary; drug therapy; Humans; Hydrogels; Infant; Infant, Newborn; Male; Propranolol; administration & dosage; therapeutic use; Skin Neoplasms; drug therapy; Treatment Outcome
- From: Chinese Journal of Plastic Surgery 2013;29(1):25-28
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo evaluate the efficacy and security of propranolol gel in treatment of Infantile hemangiomas.
METHODS51 consecutive infants with hemangiomas from October 2010 to September 2011 in Department of General Surgery Fuzhou General Hospital of Nanjing Military Command were treated with propranolol hydrochloride 3% gel. Changes in hemangioma size, texture, color, tumor blood flow peak were recorded.
RESULTSThe results were evaluated using Achauer system, responses of IHs to propranolol were considered scale I (poor) in 4 patient (17.24%), scale II (moderate) in 18 patients (24.14%), scale III (good) in 22 patients (44.83%) and scale IV (excellent) in 7 patients (13.79%). The response of superficial hemangiomas was significantly better than other hemangiomas (P < 0.05), and no significant differences in response among different primary sites (P > 0.05).
CONCLUSIONSTopical use of propranolol hydrochloride 3% gel is an effective option for superficial hemangiomas.
