Effect of sildenafil citrate on penile erection of rhesus macaques.
- Author:
Xun-Bin HUANG
1
;
Cheng-Liang XIONG
;
Cheng-Gao YU
;
Jie-Ling ZHOU
;
Ji-Yun SHEN
Author Information
- Publication Type:Journal Article
- MeSH: Animals; Electromyography; Macaca mulatta; Male; Penile Erection; drug effects; physiology; Penis; anatomy & histology; drug effects; Piperazines; pharmacology; Purines; Sildenafil Citrate; Sulfones; Vasodilator Agents; pharmacology
- From: Asian Journal of Andrology 2004;6(3):233-235
- CountryChina
- Language:English
-
Abstract:
AIMTo examine the effect of sildenafil citrate on penile erection of male rhesus macaque.
METHODSTwenty Macaca mulatta were divided into the sildenafil treated and the control groups of 10 animals each. The penile size, the corpus cavernosal electromyogram (EMG) and the intra-corpus cavernosal pressure (ICP) were determined.
RESULTSThe diameter of penis and the ICP were significantly increased and the corpus cavernosal EMG significantly reduced in the sildenafil group.
CONCLUSIONSildenafil citrate increases the penile size and ICP and reduces the corpus cavernosal EMG in male rhesus macaque.
