CT evolution of nasal steroid management of chronic rhinosinusitis.
- Author:
Luo ZHANG
1
;
Cheng-shuo WANG
;
De-min HAN
;
Bing ZHOU
;
Xiang-dong WANG
;
Wen-tong GE
;
Yun-chuan LI
;
Tong WANG
Author Information
- Publication Type:Clinical Trial
- MeSH: Adolescent; Adult; Child; Chronic Disease; Female; Humans; Male; Middle Aged; Paranasal Sinuses; diagnostic imaging; Sinusitis; diagnostic imaging; drug therapy; Steroids; administration & dosage; therapeutic use; Tomography, X-Ray Computed; Treatment Outcome
- From: Chinese Journal of Otorhinolaryngology Head and Neck Surgery 2007;42(9):673-678
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo evaluate the efficacy of topical steroid treatment of nonpolypoid chronic sinusitis.
METHODSTwo cohorts of adult and children with nonpolypoid chronic sinusitis were investigated. The first cohort consisted of 11 pediatric patients [mean age, (11.8 +/- 3.2) years] with a mean Lund score of 10.3 +/- 5.7 (x +/- s). The second cohort consisted of 13 adult patients [mean age, (36.7 +/- 11.0) years] with a mean Lund score of 12.2 +/- 5.7. The mean duration of the nasal budesonide (Rhinocort) treatment was (7.5 +/- 3.2) weeks for adult patients (256 microg/d) and (7.0 +/- 3.4) weeks for pediatric patients (128 microg/d). Each Lund score and the patient's assessment of nasal symptoms were evaluated after treatment.
RESULTSThe average Lund score was significantly decreased to 6.5 -/+ 7.5 (t = 3.82, P < 0.01) in adult patients and to 2.6 +/- 3.7 (t = 5.08, P < 0.01) in pediatric patients after treatment. Thirty-eight percent of the adult patients and 73% of the pediatric patients were cured on CT images. The patient's self-assessment of efficacy was positively correlated with pretreatment Lund score in adult patients (r = 0.676, P < 0.05), but not so in pediatric patients.
CONCLUSIONSThese findings demonstrate that most of patients with nonpolypoid chronic sinus did well with topical steroid treatment. Therefore, surgery was required in few patients.
