Applications of metabonomics in clinical diagnosis.
- Author:
Zhong-Ying LIN
1
;
Shi-Kai YAN
;
Wei-Xing DAI
;
Yun YANG
;
Hui-Zi JIN
;
Chuan ZHANG
;
Wei-Dong ZHANG
Author Information
1. Modern Research Center for Traditional Chinese Medicine, School of Pharmacy, Second Military Medical University, Shanghai 200433, China.
- Publication Type:Journal Article
- MeSH:
Biomarkers;
metabolism;
Body Fluids;
metabolism;
Diagnostic Techniques and Procedures;
Humans;
Metabolome;
Metabolomics;
methods;
Models, Theoretical;
Multivariate Analysis
- From:
Acta Academiae Medicinae Sinicae
2007;29(6):811-817
- CountryChina
- Language:Chinese
-
Abstract:
Metabonomics, as a newly developed technique, is expected to be a powerful technique in clinical diagnosis. Metabonomics-based diagnosis involves the global metabolic analysis of body-fluids, determination of biomarkers by multivariate statistic analysis, and establishemen of mathematic models for clinical diagnosis with the aid of pattern recognition. This article reviews the adoption of various analytical and computational strategies, application of metabonomics in clinical diagnosis, and potential challenges and development trends.
