Clinical characteristics of methicillin-resistant Staphylococcus aureus in phlegm specimens.
- Author:
Gui-Ping LI
1
;
Jiong ZHOU
;
Ai WANG
;
Hong-Li SUN
;
Xiao-Jun MA
;
Ying-Chun XU
Author Information
- Publication Type:Journal Article
- MeSH: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; therapeutic use; Child; Child, Preschool; Cross Infection; drug therapy; microbiology; Drug Resistance, Multiple, Bacterial; Female; Humans; Infant; Male; Methicillin-Resistant Staphylococcus aureus; drug effects; isolation & purification; Middle Aged; Respiratory Tract Infections; drug therapy; microbiology; Retrospective Studies; Sputum; microbiology; Staphylococcal Infections; drug therapy; microbiology; Young Adult
- From: Acta Academiae Medicinae Sinicae 2008;30(5):531-534
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo investigate the clinical characteristics of methicillin-resistant Staphylococcus aureus (MRSA) in phlegm specimens of positive patients, so as to provide evidences for the nosocomial infection control.
METHODSWe retrospectively analyzed the clinical data of 211 hospitalized patients who were MRSA-positive in their phlegm specimens in PUMC Hospital from January 2005 to October 2007.
RESULTSAmong the 211 patients, 196 (92.9%) had received antibiotics three months before the detection of MRSA, and 128 (60.7%) had received more than three antibiotics. Over 90% of MRSA were resistant to levofloxacin, erythromycin, clindamycin, and gentamicin, and 73.9% were resistant to rifampicin.
CONCLUSIONSImproper use of antibiotics should be avoided. Vancomycin is the first choice for MRSA treatment.
