Decreased gastric body mucosa obestatin expression in abdominal obesity patients with normal body mass index.

Author: Xin Yuan GAO ¹ ; Hong Yu KUANG ¹ ; Xiao Min LIU ¹ ; Zhi Bin MA ²
Author Information

1. Department of Endocrinology, The First Clinical Hospital of Harbin Medical University, Harbin 150001, Heilongjiang, China.
2. Department of Gastroenterology, The First Clinical Hospital of Harbin Medical University, Harbin 150001, Heilongjiang, China.
Publication Type:Letter
MeSH: Adult; Body Mass Index; Case-Control Studies; Female; Gastric Mucosa; metabolism; Humans; Male; Middle Aged; Obesity, Abdominal; metabolism
From: Biomedical and Environmental Sciences 2014;27(5):385-387
CountryChina
Language:English
Abstract: The aim of the study was to investigate whether the expression of obestatin in gastric body mucosa in abdominal obesity patients with normal body mass index (BMI) is different compared with healthy controls. Twenty abdominal obesity patients with normal BMI and twenty healthy controls were included in the study. The number of obestatin-positive cells in gastric body mucosa was significantly lower in abdominal obesity patients with normal BMI than that in healthy subjects. There was a positive correlation between the numbers of obestatin-positive cells in the gastric body mucosa and plasma obestatin levels in abdominal obesity subjects and control group.