Characteristics of continuous spike-and-wave during slow wave sleep syndrome in children.
- Author:
Lian WANG
1
;
Yan-Chun DENG
;
Yong-Hong LIU
;
Yuan-Gui HUANG
Author Information
- Publication Type:Journal Article
- MeSH: Adolescent; Child; Electroencephalography; Humans; Sleep; physiology; Status Epilepticus; diagnosis; drug therapy; physiopathology; Syndrome
- From: Chinese Journal of Contemporary Pediatrics 2010;12(2):93-95
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVEContinuous spike-and-wave during slow wave sleep (CSWS) syndrome is one of the presentations of electrical status epilepticus during sleep (ESES). The purpose of this study was to investigate the characteristics of CSWS syndrome in children.
METHODSBetween 2007 and 2009, a total of 778 nocturnal long-term or 24-hr video-EEG records were included. The EEG, clinical and neuroimaging characteristics were studied in children who met standard criteria for CSWS.
RESULTSNine children met standard criteria for CSWS in video-EEGs. Their ages ranged 6 to 13 years. Their EEGs were characterized by continuous spike-and-wave (SW) discharges during non-rapid eye movement (NREM) sleep, accounting for 85%-100% of the period of NREM sleep. Clinically, these children had various types of epileptic seizures and exhibited different degrees of neuropsychiatric impairments, language dysfunction, and/or behavioral disturbances. Neuroimaging abnormalities were found in 6 cases, including atelencephalia or atrophy, gray matter heterotopia and leucomalacia.
CONCLUSIONSThis study indicates the characteristics of CSWS syndrome in clinical manifestations, EEG and neuroimaging examinations. This will be helpful in understanding CSWS syndrome.
