DRD2/ANKK1 Taq IA polymorphism and early infant temperament.
- Author:
Jing MA
1
;
Chun-Xiang HUANG
;
Pi-Xiang PI
;
Ai-Bin XIA
;
Lin-Yan SU
Author Information
- Publication Type:Journal Article
- MeSH: Genotype; Humans; Infant; Polymorphism, Genetic; Protein-Serine-Threonine Kinases; genetics; Receptors, Dopamine D2; genetics; Temperament
- From: Chinese Journal of Contemporary Pediatrics 2010;12(2):106-109
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo investigate whether there is an association between DRD2/ANKK1 Taq IA polymorphism and early infant temperament.
METHODSDRD2/ANKK1 Taq IA polymorphism (rs1800497) was determined using polymerase chain reaction-ligase detection reaction (PCR-LDR) techniques in 149 Chinese Han infants from Changsha City. Their mothers were asked to complete the Early Infant Temperament Questionnaires (EITQ) when the infants were 1 to 4 months old (mean: 2.75 months). There were three genotypes found in these infants: C/C, T/T and C/T. The subjects were subdivided into T-carrier (CT, TT) and non-T-carrier (CC) groups for statistical analysis.
RESULTSThere were no differences in the temperament style distribution between the T-carrier and non-T carrier groups. There were also no statistically significant differences between the two groups in the score of the nine temperament dimensions.
CONCLUSIONSDRD2/ANKK1 Taq IA polymorphism is not associated with early infant temperament.
