Concentrations of granulocyte colony-stimulating factor in children with moyamoya disease.
- Author:
Ming-Sheng MA
1
;
Li-Ping ZOU
;
Ying-Xue DING
;
Hong JIN
Author Information
- Publication Type:Journal Article
- MeSH: Child; Child, Preschool; Female; Granulocyte Colony-Stimulating Factor; blood; physiology; Humans; Male; Moyamoya Disease; blood; etiology; Vascular Endothelial Growth Factor A; analysis; physiology
- From: Chinese Journal of Contemporary Pediatrics 2010;12(2):117-119
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo explore the roles of granulocyte colony-stimulating factor in the pathogenesis of moyamoya disease.
METHODSSerum G-CSF concentrations were measured using enzyme linked immunosorbent assay (ELISA) in 20 children with moyamoya disease and 20 healthy children.
RESULTSSerum G-CSF concentration (35.7+/-10.3 pg/mL) in children with moyamoya disease was significantly higher than that in healthy controls (23.5+/-3.8 pg/mL) (p<0.01).
CONCLUSIONSThe elevated serum G-CSF concentration in children with moyamoya disease suggests that G-CSF may play an important role in the pathogenesis of moyamoya disease.
