Application of endotracheal lavage in neonatal ventilator-associated pneumonia.
- Author:
Xin-Zhu LIN
1
;
Chang-An OU-YANG
;
Ji-Dong LAI
;
Ya-Dan LI
;
Zhi ZHENG
Author Information
- Publication Type:Journal Article
- MeSH: Female; Humans; Incidence; Infant, Newborn; Male; Pneumonia, Ventilator-Associated; epidemiology; therapy; Respiration, Artificial; statistics & numerical data; Therapeutic Irrigation; methods; Trachea
- From: Chinese Journal of Contemporary Pediatrics 2010;12(3):195-197
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo study the efficacy of endotracheal lavage in neonatal ventilator-associated pneumonia (VAP).
METHODSFifty-eight neonates with VAP between January 2002 and December 2008 were randomly assigned to two groups: lavage and control (n=29 each). After withdrawal from ventilator, both groups received sensitive antibiotics therapy according to sputum culture results as well as supportive treatment. The lavage group was additionally treated with endotracheal lavage (2-3 times daily). The therapeutic effects were compared between the two groups.
RESULTSThere were no significant differences in the average time of mechanical ventilation between the lavage and the control groups. The effective rate in the lavage group (93%) was significantly higher than that in the control group (69%; p<0.05). Three percent of patients in the lavage group required twice or more mechanical ventilation compared with 24% in the control group (p<0.05). Blood gas analysis results were obviously improved in the lavage group 2 hrs after treatment (p<0.01).
CONCLUSIONSEndotracheal lavage can decrease the number in mechanical ventilation and improve therapeutic effects in neonates with VAP.
