Detection of cardiac troponin and high-sensitivity C reactive protein in children with viral myocarditis.
- Author:
Jiong-Guang GUO
1
Author Information
- Publication Type:Journal Article
- MeSH: Biomarkers; blood; C-Reactive Protein; metabolism; Child; Child, Preschool; Creatine Kinase, MB Form; blood; Female; Humans; Male; Myocarditis; blood; virology; Troponin T; blood; Virus Diseases; blood
- From: Journal of Southern Medical University 2008;28(6):1076-1077
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo investigate the changes of cardiac T troponin (cTnT) and high-sensitivity C reactive protein (hs-CRP) in children with viral myocarditis (VMC).
METHODSForty children with VMC were examined for cTnT, hs-CRP, and creatine kinase MB (CK-MB) levels.
RESULTSChildren with VMC had significantly higher cTnT, hs-CRP and CK-MB levels than the control group on admission (P<0.01), but obviously decreased after two weeks of treatment. The positivity rate of cTnT and hs-CRP were significantly higher in children with VMC than the control group on admission, and decreased significantly after treatment (P<0.01). The positivity rate of cTnT and hs-CRP were significantly higher than that of CK-MB (P<0.05).
CONCLUSIONSerum cTnT and hs-CRP are sensitive indices for diagnosis of VMC, and their detection have important value in estimation of the patients' condition.
