Clinical investigation of delayed graft function recovery following renal transplantation.
- Author:
Hai-Peng YI
1
;
Li-Xin YU
Author Information
- Publication Type:Journal Article
- MeSH: Adult; Delayed Graft Function; physiopathology; therapy; Female; Graft Rejection; physiopathology; therapy; Graft Survival; Humans; Immunosuppressive Agents; therapeutic use; Kidney Transplantation; Male; Recovery of Function; Renal Dialysis; Retrospective Studies
- From: Journal of Southern Medical University 2008;28(6):1088-1089
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo investigate the etiology and therapy of delayed graft function (DGF) recovery in renal transplant recipients.
METHODSThe clinical data were retrospectively analyzed in 15 renal recipients with DGF. All the 15 patients received hemodialysis along with pulse treatment against acute rejection (AR), or immunosuppressant adjustment, or in situ retransplantation after the resection of the original transplanted kidney according to different etiological factors.
RESULTSAmong the 15 patients, 8 developed AR, 5 showed acute renal tubular necrosis (ATN), 1 had grafting-associated renal vein embolism and 1 had acute cyclosporine nephrotoxication. The renal function recovered within 10 to 35 days after transplantation without complication during the follow-up period (0.5-3.0 years).
CONCLUSIONDGF is a common complication after kidney transplantation mainly due to the occurrence of AR and ATN. Good prognosis is expected if etiology-oriented therapy is performed properly and promptly.
