Observation on effect of compound danshen droplet-pill combined with trimetazidine in treating senile unstable angina pectoris.
- Author:
Zhong-xia QIU
1
;
He-jun MA
;
Di-fei WANG
Author Information
- Publication Type:Journal Article
- MeSH: Aged; Aged, 80 and over; Angina, Unstable; drug therapy; Drug Administration Schedule; Drug Therapy, Combination; Drugs, Chinese Herbal; therapeutic use; Female; Humans; Male; Middle Aged; Phenanthrolines; therapeutic use; Phytotherapy; Trimetazidine; therapeutic use; Vasodilator Agents; therapeutic use
- From: Chinese Journal of Integrated Traditional and Western Medicine 2005;25(9):787-789
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo investigate the effect of compound Danshen Droplet-pill (DS) combined with trimetazidine (TMZ) in treating senile unstable angina pectoris (SUAP).
METHODSOne hundred and twenty patients with SUAP were eaually and randomly divided into 2 groups, the treated group and the control group. Changes of angina, occurrence of arrhythmia, myocardial infarction and sudden death, myocardial ischemia in ECG and partial indexes of heart function were observed.
RESULTSThe total effective rate in the treated group was 78.3%, while that in the control group was 53.3%, comparison of the two groups showed significant difference (P < 0.05). The incidence rate of arrhythmia in the two groups was 18.2% and 30.0% respectively and that of acute myocardial infarction and sudden death was 0 and 5.0% respectively, also showed significant difference between them (P < 0.05). Condition of myocardial ischemia revealed in ECG and partial indexes of heart function in the treated group were all improved to certain extent. Conclusion DS combined with TMZ is superior in treating SUAP.
