Effect of Chinese herbal medicine on patients with primary hepatic carcinoma in III stage during perioperational period: a report of 42 cases.
- Author:
Li-Wu CHEN
1
;
Jing LIN
;
Wen CHEN
;
Weiping ZHANG
Author Information
- Publication Type:Journal Article
- MeSH: Adult; Animals; Carcinoma, Hepatocellular; drug therapy; immunology; mortality; surgery; Combined Modality Therapy; Drug Administration Schedule; Drugs, Chinese Herbal; therapeutic use; Female; Humans; Liver Neoplasms; drug therapy; immunology; mortality; surgery; Male; Middle Aged; Phytotherapy; Survival Rate
- From: Chinese Journal of Integrated Traditional and Western Medicine 2005;25(9):832-834
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo investigate the synergetic effect of general therapy of Chinese herbal medicine with surgical operation.
METHODSFourty-two patients in the integrative group were treated with jiedu xiaozheng yin for 7 days before operation, and fuzheng yiliu recipe after operation for 2 years, and 30 patients in the control group underwent operation alone. Their cellular immune function, survival rate and recurrence rate were compared and analyzed.
RESULTSThe accumulative survival rate of 6-month, 12-month, 24-month and 36-month in the integrative group was 97.6%(41/42), 85.7%(36/42), 52.3% (22/42) and 45.5(17/42)% respectively and those in the control group 96.7% (29/30), 83.3% (25/30), 50.0% (15/30) and 30.0% (9/30), respectively, among them the 36-month survival rate was significantly different between the two groups (P < 0.05). The 24-month recurrence rate in the two groups was 54.8% and 80.0% respectively, the difference between the two was significant (P < 0.05).
CONCLUSIONAdministration of compound Chinese herbal medicine in peri-operational period has definite effect on primary hepatic carcinoma in III stage, it can improve patients' immune function, decrease the recurrence rate and increase the cumulative survival rate.