A Case of Adult-onset Henoch-Schonlein Purpura (HSP) Combined with Post-infectious Glomerulonephritis (PIGN).
- Author:
Kyoung Min MOON
1
;
Joo Hyung KANG
;
Dong Gyu KIM
;
Woong Chul LEE
;
Yu Ri MOON
;
Jong Eun JOO
;
Yong Il KIM
;
Seoung Oh YANG
;
Young Sook LEE
Author Information
1. Department of Internal Medicine, Eulji University Hospital, Eulji University School of Medicine, Daejeon, Korea. visionjcys@eulji.ac.kr
- Publication Type:Case Report
- Keywords:
Purpura;
Schoenlein-Henoch;
Glomerulonephritis;
Complement system proteins
- MeSH:
Adult;
Child;
Complement System Proteins;
Electrons;
Glomerulonephritis;
Humans;
Immunoglobulin A;
Joints;
Kidney;
Nephritis;
Prognosis;
Purpura;
Purpura, Schoenlein-Henoch;
Skin;
Vasculitis
- From:Korean Journal of Nephrology
2008;27(4):518-523
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Henoch-Schonlein purpura (HSP) is a small-vessel vasculitis that are predominantly observed in children, affecting their skin, joints, gut and kidneys. The renal prognosis of HS nephritis is known to be worse in adults than in children. It is defined by tissue deposition of IgA. In most HSP patients, serum complement levels are usually normal. However, some authors reported abnormalities of serum complement levels in children-onset HSP. The authors report here a rare adult-onset case of HSP combined with post-infectious glomerulonephritis, especially hypocomplementemia and subepithelial 'hump'- like electron dense deposits.
