Thinking and challenge induced by the hypothesis of breaking stagnant and eliminating blood stasis in Treating acute cerebral hemorrhage by rF VII a.
- Author:
Jian-wen GUO
1
;
Ye-feng CAI
;
Bao-xin DU
Author Information
1. ment of Neurology, Guangdong Provincial Hospital of Traditional Chinese Medicine, Guangzhou. guojianwen1008@yahoo.com.cn
- Publication Type:Journal Article
- MeSH:
Cerebral Hemorrhage;
drug therapy;
Drugs, Chinese Herbal;
therapeutic use;
Factor VIIa;
biosynthesis;
genetics;
therapeutic use;
Humans;
Medicine, Chinese Traditional;
Phytotherapy;
Recombinant Proteins;
biosynthesis;
genetics;
therapeutic use
- From:
Chinese Journal of Integrated Traditional and Western Medicine
2005;25(11):1027-1029
- CountryChina
- Language:Chinese
-
Abstract:
Definite therapeutic effect has obtained by TCM in treating acute cerebral hemorrhage (ACH) according the TCM theory of "blood circulating outside the vessels is the stasis" using breaking stagnant and eliminating blood stasis (Poxue Zhuyu) method, but no material involving the natural development of stoke in superacue stage (0 - 4 hrs after onset of the disease) being presented so far. It has been proved by randomized, double-blinded multi-centeric clinical trials that recombinant activated factor VII (rF VII a) could decreased the morbidity and disability of patients suffered from ACH, suggesting that use hemostasis treatment in ACH during superacu stage should be stressed, and the drugs for Poxue Zhuyu should be used cautiously in the period of 0 - 4 hrs after onset. The hemorrhagic disorder could be eliminated by using drugs for Poxue Zhuyu and other medicines in rational combination.
