Refractory Granulomatosis with Polyangiitis Presenting as Facial Paralysis and Bilateral Sudden Deafness.
- Author:
Sang Hoon KIM
1
;
A Ra JUNG
;
Su Il KIM
;
Seung Geun YEO
Author Information
- Publication Type:Case Report
- Keywords: Granulomatosis with polyangiitisis; Bilateral hearing loss; Facial paralysis; Rituximab
- MeSH: Deafness; Facial Paralysis*; Granuloma; Hearing Loss, Bilateral; Hearing Loss, Sensorineural; Hearing Loss, Sudden*; Humans; Respiratory System; Rituximab; Vasculitis; Vertigo
- From:Journal of Audiology & Otology 2016;20(1):55-58
- CountryRepublic of Korea
- Language:English
- Abstract: Granulomatosis with polyangiitisis [(GPA) or Wegener granulomatosis] is a multi-system disease characterized by granuloma formation and necrotizing vasculitis. GPA classically shows involvement of the respiratory tracts and the renal system. However, locoregional disease is common and may include otologic manifestations. Although otologic involvement can occur during the course of GPA, no report has described facial palsy with sudden sensorineural total deafness with vertigo as the presenting feature of GPA. This case describes a patient with multiorgan involving resistant form of GPA initially presenting with bilateral profound sudden sensorineural hearing loss and left facial paralysis with vertigo. The condition responded well to treatment with rituximab.
