A case of Klinefelter's syndrome with type 1 diabetes mellitus.
- Author:
Xiao-pin CAI
1
;
Li ZHAO
;
Min MAO
;
Zhao-jun YANG
;
Xiao-yan XING
;
Guang-wei LI
Author Information
1. Graduate School of Peking Union Medical College, Chinese Academy of Medical Sciences, and Department of Endocrinology, China-Japan Friendship Hospital, Beijing 100730, China.
- Publication Type:Journal Article
- MeSH:
Adult;
Diabetes Mellitus, Type 1;
diagnosis;
etiology;
Humans;
Klinefelter Syndrome;
complications;
diagnosis;
Male;
Young Adult
- From:
Chinese Medical Journal
2012;125(5):937-940
- CountryChina
- Language:English
-
Abstract:
Klinefelter’s syndrome (KS) is the most common sex chromosome disease in men. Classical features of the syndrome include a eunuchoidal body habitus, small testes and hypergonadotrophic hypogonadism. There has been an increased risk of diabetes mellitus and autoimmune disease for KS patients. This paper reports a case of KS in association with type 1 diabetes mellitus. The patient was a 21-year-old man, who has been confirmed by absolute insulin deficiency and positive IA-2 autoantibody. The hyperinsulinemic euglycemic clamp test indicated his insulin sensitivity in normal range, and his blood glucose was controlled well by the insulin therapy.
