Use of covered Cheatham-Platinum stent as the primary modality in the treatment for native coarctation of the aorta.
- Author:
Zong-ping CHANG
1
;
Shi-liang JIANG
;
Zhong-ying XU
;
Ge-jun ZHANG
;
Lian-jun HUANG
;
Shi-hua ZHAO
;
Jian LING
;
Hong ZHENG
;
Jing-lin JIN
;
Wen-hui WU
;
Hai-bo HU
;
Shi-guo LI
;
Ji-hong YU
;
Chao-wu YAN
Author Information
- Publication Type:Journal Article
- MeSH: Adolescent; Adult; Angioplasty, Balloon; Aortic Coarctation; pathology; physiopathology; therapy; Female; Humans; Male; Middle Aged; Platinum; Stents; adverse effects; Systole
- From: Chinese Medical Journal 2012;125(6):1005-1009
- CountryChina
- Language:English
-
Abstract:
BACKGROUNDBare stent implantation in the treatment for native and recurrent coarctation of the aorta (CoA) has become established as an alternative to surgery and balloon angioplasty. However, this modality still encounters significant complications during the procedure and/or follow-up. The covered Cheatham-Platinum (CP) stent commonly used to be chosen as a rescue treatment in these patients. The purpose of this study was to evaluate the use of covered CP stent as the primary modality in the treatment for native CoA.
METHODSTwenty-five covered CP stents and 2 bare CP stents were implanted in 25 patients with native CoA. All patients after the intervention were invited for follow-up examinations.
RESULTSThe peak systolic gradient across the lesion decreased significantly from a median value of 67.5 mmHg (quartile range, 19.3 mmHg) to 2 mmHg (quartile range, 4.0 mmHg) (P < 0.0001). Stenotic segment diameter increased from a median value of 5.0 mm (quartile range, 1.5 mm) to 17.9 mm (quartile range, 2.5 mm) (P < 0.0001). The median ratio of diameter of the coarctation postprocedure to preprocedure was 4.2 (quartile range, 1.6). All of the CP stents were placed in the suitable position without any acute complications. During a follow-up period of up to 72 months, no complications were encountered. Most of the patients (21/25) were normotensive, apart from four patients requiring antihypertensive medication during the follow-up.
CONCLUSIONThe implantation of covered CP stent as the primary modality is safe and effective in the treatment for native CoA in adolescents and adults.