Survey on the recessive infection of pathogen to hand-foot-mouth disease among healthy adults and children in Guangdong province
10.3760/cma.j.issn.0254-6450.2012.02.014
- VernacularTitle:广东省健康人群手足口病病原隐性感染状况调查
- Author:
Ai-Ping DENG
1
;
Yong-Hui ZHANG
;
Li-Mei SUN
;
Han-Ri ZENG
;
Wei LI
;
Chang-Wen KE
;
Jian-Feng HE
;
Cong MA
;
Jin-Yan LIN
Author Information
1. 广东省疾病预防控制中心
- Keywords:
Enterovirus 71;
Coxsackie virus A16;
Hand-foot-mouth disease;
Recessive infection
- From:
Chinese Journal of Epidemiology
2012;33(2):189-191
- CountryChina
- Language:Chinese
-
Abstract:
Objective To understand the pathogen-carrying status of hand-foot-mouth disease (HFMD) among healthy people in Guangdong province.Methods Stool specimens were collected randomly on 7 age groups from 7 cities in Guangdong province.Real-time RT-PCR was used to detect enterovirus (EV),enterovirus 71 (EV71) and coxsackie virus A16 (CA16).Results Altogether,1285 stool specimens were collected.The positive rates of EV71,CA16 and other enterovirus were 0.39％ (5/1285),0.23％ (3/1285) and 7.00％ (90/1285),respectively.The highest EV71 positive rate (1.79％) was among the 4-6-year-old group,followed by the age group 0-3 with positive rate as 0.67％.EV71 was not found among the rest age groups.The highest CA16 positive rate (1.35％) was among the 4-6 year-olds group,but the CA16 was not found among the rest age groups.EV71 was only found among native population,with the positive-rate as 0.47％.CA16-positive rate was 0.19％ among the native population and 0.85％ among floating population,with no significant difference found (P＞0.05).The EV71 positive rate was 0.36％ among rural residents and 0.54％ among urban residents,but with no significant difference (P＞0.05).All CA16 was found among the urban residents.Conclusion Recessive infection of EV71 and CA16 were only found among 0-6 year-old group but not found among other groups,which suggested that the approaches on prevention and control should be targeted to all children especially on pre-school children.
