Resection A Surgery: An Exclusion Criterion of Adjuvant Treatment for Gastric Cancer.
10.4174/jkss.2010.79.3.196
- Author:
Wansik YU
1
;
Ho Young CHUNG
Author Information
1. Department of Surgery, School of Medicine, Kyungpook National University, Daegu, Korea. wyu@knu.ac.kr
- Publication Type:Original Article
- Keywords:
Stomach neoplasm;
Quality of surgery;
Adjuvant chemotherapy
- MeSH:
Chemotherapy, Adjuvant;
Gastrectomy;
Humans;
Lymph Nodes;
Multivariate Analysis;
Neoplasm Metastasis;
Prognosis;
Retrospective Studies;
Stomach Neoplasms;
Survival Rate
- From:Journal of the Korean Surgical Society
2010;79(3):196-201
- CountryRepublic of Korea
- Language:English
-
Abstract:
PURPOSE: We evaluated the clinical implication of Resection A surgery retrospectively to identify whether quality of surgery can be used as a selection factor for adjuvant therapy in patients with gastric cancer. METHODS: Prognosis of 902 patients with gastric cancer who underwent Resection A surgery was evaluated. RESULTS: Among all discharged patients, 77 patients (8.5%) died of recurrent disease, 55 patients (6.1%) died without recurrent disease. Five-year survival rate of all discharged patients was 91.6% and 10-year survival rate 87.1%. Statistically significant prognostic factors were depth of invasion (P<0.001), lymph node metastasis (P<0.001), stage (P<0.001), tumor location (P=0.036) and size (P=0.001), extent of gastric resection (P<0.001), and chemotherapy (P<0.001) on univariate analyses. However, depth of invasion (P=0.001), lymph node metastasis (P<0.001), and total gastrectomy (P<0.001) emerged as statistically significant poor prognostic factor on a multivariate analysis. Adjuvant chemotherapy did not increase the survival rate of patients after Resection A surgery, even in patients with stage II disease. CONCLUSION: In selecting the patients for adjuvant therapy, both the stage of gastric cancer and the quality of surgery should be considered.
