Effect of Fructus Bruceae oil emulsion on cellular immune function and quality of life in patients with non-small cell lung cancer.
- Author:
Hua-Qin TIAN
1
;
Shou-Yi YU
;
Bin WANG
Author Information
- Publication Type:Journal Article
- MeSH: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; therapeutic use; Brucea; chemistry; Carcinoma, Non-Small-Cell Lung; drug therapy; immunology; Drugs, Chinese Herbal; administration & dosage; Emulsions; Female; Fruit; chemistry; Humans; Immunity, Cellular; drug effects; Lung Neoplasms; drug therapy; immunology; Male; Middle Aged; Phytotherapy; Quality of Life; Treatment Outcome
- From: Chinese Journal of Integrated Traditional and Western Medicine 2007;27(2):157-159
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo observe the effect of Fructus Bruceae oil emulsion (FBE) on cellular immune function (CIF) and quality of life (QOF) in patients with non-small cell lung cancer (NSCLC) after chemotherapy.
METHODSOne hundred and fifteen patients with mid-late stage NSCLC were randomly assigned to two groups, the 57 patients in the control group were only treated with chemotherapy of GP regimen, 58 in the treatment group with the chemotherapy of the same regimen and combined with FBE. The clinical efficacy was evaluated after two cycles of chemotherapy.
RESULTSThe effective rate was 51.8% and 47.4% in the treatment group and the control group respectively, the difference between them was insignificant (P > 0.05). CIF and QOF in the treatment group were better than those in the control group after chemotherapy respectively (P < 0.01), in the latter, CIF and QOF were desreased after chemotherapy (P < 0.05).
CONCLUSIONFBE combined with chemotherapy can improve the cellular immune function and quality of life in patients with mid-late stage NSCLC.
