Distribution and Antimicrobial Resistance of Streptococcus pneumoniae at Four University Hospitals in Busan and Gyeongnam.
- Author:
Si Hyun KIM
1
;
Sae Am SONG
;
Jongyoun YI
;
Duyeal SONG
;
Chulhun Ludgerus CHANG
;
Dong Chul PARK
;
Sang Hwa URM
;
Hye Ran KIM
;
Jeong Hwan SHIN
Author Information
- Publication Type:Original Article
- Keywords: Drug resistance; Multiple; Streptococcus pneumoniae
- MeSH: Busan*; Cefotaxime; Ceftriaxone; Clindamycin; Drug Resistance; Erythromycin; Hospitals, University*; Humans; Korea; Levofloxacin; Penicillins; Pneumonia; Streptococcus pneumoniae*; Streptococcus*
- From:Annals of Clinical Microbiology 2016;19(2):48-53
- CountryRepublic of Korea
- Language:Korean
- Abstract: BACKGROUND: Streptococcus pneumoniae is the most common human pathogen causing community-acquired pneumonia. There is little information on the recent antimicrobial susceptibility patterns of S. pneumoniae in Busan and Gyeongnam of Korea. The aim of this study was to investigate the distribution and antimicrobial resistance of S. pneumoniae at 4 university hospitals in Busan and Gyeongnam. METHODS: We collected and analyzed the antimicrobial susceptibility results of 850 S. pneumoniae strains isolated from regional 4 university hospitals during the last 2 years from July 2013 through June 2015. RESULTS: Among 850 S. pneumoniae strains, 635 strains were isolated from respiratory specimens, followed by blood (N=121), CSF (N=13), and others (N=81). Antimicrobial susceptibility rates to penicillin, cefotaxime and ceftriaxone were 79.4%, 76.6% and 83.6%, respectively. The resistant rates to erythromycin and clindamycin were 80.9% and 68.2%, respectively. The resistant rates to levofloxacin were 9.2%. There were some differences in resistant rates by age groups, years, and specimen types. CONCLUSION: We found the changes of antimicrobial resistance of S. pneumoniae during the last 2 years. It is necessary to monitor the antimicrobial susceptibility of S. pneumoniae regularly for empirical therapy and for early detection of the changes of resistance.
