Effect of banxia xiexin decoction and its components on coefficient of variability of slow wave electrogastric rhythm in rats with electrogastric dysrhythmia.
- Author:
Yu-hang LI
1
;
Qing-guo WANG
;
Meng CHEN
Author Information
- Publication Type:Journal Article
- MeSH: Animals; Digestive System; drug effects; physiopathology; Electrodiagnosis; Gastrointestinal Motility; drug effects; Medicine, Chinese Traditional; Myoelectric Complex, Migrating; drug effects; Plant Extracts; pharmacology; Rats; Stomach Diseases; physiopathology
- From: Chinese Journal of Integrated Traditional and Western Medicine 2006;26 Suppl():53-55
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo observe the effect of Banxia Xiexin Decoction (BD) and its components in the rats with electrogastric dysrhythmia, explore the mechanism of BD' s "relieving distension and fullness, and dissolving lumps" and study BD' s compatibility regularity.
METHODSRat model of electrogastric dysrhythmia was established, the effects of BD and its components on the coefficient of variability of the model' s slow wave electrogastric rhythm were determined.
RESULTSCompared with the model group, BD and all the components groups had better effects on all the aspects (P <0. 05 ), Among which the group containing herbs with pungent and bitter flavour (Rhizoma Pinelliae, Rhizoma Zingiberis, Radix Scutellariae, Radix Berberidis julianae) was the best.
CONCLUSIONBD and all the components have the effects of rectifying electrogastric dysrhythmias in various degrees, and the herbs with pungent and bitter flavour are best. This study provides the experimental foundations for further understanding the mechanism of BD' s treating principle-using bitter drugs for purgation and pungent drugs for dispersion, normalizing the functional activities of qi.
