Laparoscopic radical cystectomy with extended pelvic lymph node dissection for bladder urothelial carcinoma: complications and oncologic outcomes in 210 cases.
- Author:
Kai XU
1
;
Chunxiao LIU
Author Information
- Publication Type:Journal Article
- MeSH: Cystectomy; adverse effects; methods; Female; Humans; Laparoscopy; Lymph Node Excision; adverse effects; methods; Male; Middle Aged; Postoperative Complications; Survival Rate; Treatment Outcome; Urinary Bladder Neoplasms; mortality; surgery
- From: Journal of Southern Medical University 2012;32(7):1012-1015
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo investigate the complications and oncologic outcomes of 210 cases of bladder urothelial carcinoma (BUC) treated with laparoscopic radical cystectomy (LRC) with extended pelvic lymph node dissection (EPLND) and assess the feasibility and safety of this surgical technique.
METHODSFrom January, 2003 to March 2010, 210 patients with BUC underwent LRC with EPLND. The cases with positive lymph nodes or T3a disease received adjuvant chemotherapy after the operation. The complications and oncologic results were recorded and analyzed.
RESULTSThe mean operative time was 105 min in these cases with a mean blood loss of 220 ml and a rate of perioperative blood transfusion of 20.5%. The mean number of harvested lymph nodes was 17.6, and 42 (20%) cases were found to have positive lymph nodes. Minor and major perioperative complications occurred in 19% and 5.3% of the cases, respectively. The 5-year estimated overall survival, cancer-specific survival, recurrence-free survival and metastasis-free survival rates were 73.8%, 83.3%, 81.8% and 90.5%, respectively.
CONCLUSIONSLRC with EPLND is a safe and feasible technique for management of BUC and can produce satisfactory oncologic results.
