Test-bolus injection for optimization of arterial phase imaging during contrast-enhanced hepatic MR imaging.
10.3349/ymj.2000.41.4.459
- Author:
Jeong Sik YU
1
;
Ki Whang KIM
;
Byung June JO
;
Mi Gyoung JEONG
;
Jai Keun KIM
;
Jin Kyeung HAHM
;
Jong Tae LEE
;
Hyung Sik YOO
Author Information
1. Department of Diagnostic Radiology and the Research Institute of Radiological Science, Yonsei University College of Medicine, Seoul, Korea. yjsrad97@yumc.yonsei.ac.kr
- Publication Type:Original Article ; Research Support, Non-U.S. Gov't
- Keywords:
Liver MR;
liver neoplasms;
contrast enhancement MR
- MeSH:
Adult;
Aged;
Aged, 80 and over;
Female;
Hepatic Artery/pathology;
Human;
Image Enhancement*;
Liver/pathology*;
Liver Neoplasms/secondary;
Liver Neoplasms/diagnosis;
Magnetic Resonance Imaging;
Male;
Middle Age;
Time Factors
- From:Yonsei Medical Journal
2000;41(4):459-467
- CountryRepublic of Korea
- Language:English
-
Abstract:
Contrast enhancement during the dynamic MR imaging is important for the detection and characterization of focal liver lesions. The purpose of this study was to determine whether or not a timing examination with a injection of a 1.0-mL bolus of gadopentetate dimeglumine into the antecubital vein followed by rapid dynamic scanning and measurement of signal intensity of the aorta could help to obtain proper arterial-dominant phase images for the characterization of focal hepatic lesions during subsequent multiphase dynamic MR imaging. The imaging delay to acquisition of the first gadolinium-enhanced image for multiphase dynamic MR imaging was set to equal the time to peak aortic enhancement during the test examination. The first contrast-enhanced images of 80 patients with 160 focal liver lesions (hepatocellular carcinoma, n = 79; cavernous hemangioma, n = 51; metastatic tumor, n = 30) were then retrospectively reviewed. Peak aortic enhancement occurred between 10 and 28 seconds (mean, 16.5 seconds +/- 3.1) after starting the infusion of contrast material in 80 patients during the test-examination. Depending on the findings of intrahepatic vascular enhancement on the full-scale dynamic images, hepatic arterial phase (n = 11, 14%) or sinusoid phase (n = 65, 81%) imaging was obtained during the first gadolinium-enhanced acquisition in 76 (95%) of 80 patients. Three different lesions were well characterized and easily distinguished from each other (p < .0001) on the first-phase images depending on their enhancement pattern. In the majority of patients, timing examination with test-bolus injection was helpful in obtaining qualified images for the characterization of various focal lesions.
