Contribution to the study on stabilization of tablets of vitamin B1+ B6+ B12
- Author:
Duc Huu Nguyen
- Publication Type:Journal Article
- Keywords:
vitamin
- MeSH:
Vitamins;
Pharmaceutical Preparations;
tablets
- From:Pharmaceutical Journal
2000;286(2):12-15
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
To stabilize vitamin B12 in tablets containing Vitamin B1+B6+B12, Kollidon Cl-M was used as stabililizer combining with the dispersion of vitamin B12 in dry state before compression. Applying accelerated stability testing with storage condition of t0 = 570C, RH = 80% in 72 hours, the preliminary results showed that the use of Kollidon CL-M 2% in the formulation can improved effect on the stabilization of vitamin B12.