Changes in oral microflora in patients with recurrent oral ulcers.
- Author:
Jian-Zhang WANG
1
;
Qing CHEN
;
Hong SHEN
Author Information
- Publication Type:Journal Article
- MeSH: Adult; Colony Count, Microbial; Female; Humans; Male; Mouth Mucosa; microbiology; Neisseria; isolation & purification; Saliva; microbiology; Stomatitis, Aphthous; microbiology; Streptococcus; isolation & purification; Veillonella; isolation & purification
- From: Journal of Southern Medical University 2009;29(5):986-989
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo investigate the correlation between the changes in oral microflora and recurrent oral ulcers (ROU).
METHODSSalivary sample were collected from ROU patients with oral ulcers (group T) and those with ulcer healing (group C) as well as from ROU-free individuals (group N). The quantity of 3 common bacteria (Streptococcus sp., Veillonella sp., and Neisseria sp.) in the salivary samples was detected and compared between the 3 groups.
RESULTSThe quantities of Streptococcus sp. (7.30-/+0.89 copies/ml) and Veillonella sp. (8.29-/+0.77 copies/ml) in group T were significantly lower than those in group N (8.15-/+0.55 and 8.93-/+0.76 copies/ml, respectively, P<0.01), but similar with those in group C. The quantity of Streptococcus sp. (7.51-/+0.81 copies/ml) in group C was significantly lower than that in group N (8.15-/+0.55 copies/ml, P<0.01), but the quantity of Veillonella sp. was similar between the two groups. No significant difference were found in the quantity of Neisseria sp. between the 3 groups.
CONCLUSIONThe quantity of oral microflora differs significantly between patients with recurrent oral ulcers and normal individuals, suggesting a possible correlation between oral microfora and recurrent oral ulcers.
