Clinical analysis of primary thymic lymphoma: a report of 27 cases.
- Author:
Jian WANG
1
;
Wu-jun WANG
;
Hua WU
;
Hao-fei WANG
;
Zhen ZHANG
Author Information
- Publication Type:Journal Article
- MeSH: Adolescent; Adult; Aged; Aged, 80 and over; Child; Combined Modality Therapy; Female; Humans; Lymphoma; diagnosis; pathology; therapy; Male; Middle Aged; Thymus Neoplasms; diagnosis; pathology; therapy; Young Adult
- From: Journal of Southern Medical University 2009;29(5):1062-1064
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo investigate clinicopathologic features and optimal treatment of primary thymic lymphoma.
METHODSClinical records of 27 primary thymic lymphoma patients treated from 1990 to 2007 were reviewed.
RESULTSOf the 27 patients, 8 received mastectomy and chemotherapy, 12 received excision of the thymic lesion and chemotherapy, 5 received chemotherapy alone, and 2 received lesion excision alone. 24 achieved complete remission after scheduled treatment, 1 achieved partial remission, and 2 patients had progressive disease. With a follow-up of 10 years and median 38 months, the 5-year overall and disease-free survival rates of the 27 patients were 47% and 23% respectively.
CONCLUSIONThe main subtypes of primary thymic lymphoma are diffuse large B-cell lymphoma and peripheral T-cell lymphoma. The optimal sequence is radical operation followed by standard anthracycline-based regimens and radiotherapy.