Epidural butorphanol analgesia in elderly patients undergoing hip replacement.
- Author:
Dong-Hua HU
1
;
Ya-Lan LI
;
Ming-Xue CAI
;
Hui ZHANG
;
Ming-Fang XIANG
;
Bing SHUAI
;
Cai NIE
Author Information
- Publication Type:Journal Article
- MeSH: Aged; Aged, 80 and over; Analgesia, Epidural; Arthroplasty, Replacement, Hip; adverse effects; Butorphanol; administration & dosage; therapeutic use; Female; Humans; Male; Middle Aged; Morphine; administration & dosage; therapeutic use; Pain, Postoperative; etiology; prevention & control
- From: Journal of Southern Medical University 2009;29(7):1435-1437
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo evaluate the efficacy and safety of continuous epidural analgesia (CEA) with butorphanol in elderly patients undergoing hip replacement.
METHODSSixty patients scheduled for selective hip replacement were randomized into group B (n=30) to receive patient-controlled epidural analgesia (PCEA) with butorphanol and group M (n=30) to receive PCEA with morphine. Their pain distribution at 5 time points, postoperative global score and the adverse effects in 48 h were observed.
RESULTSThe pain distribution at the 5 time points or the global score for postoperative PCEA in 48 h showed no statistically significant difference between the two groups (P<0.05). Analgesia with butorphanol caused less adverse effects (respiratory depression, nausea and vomiting, itching and abdominal distension) than that with morphine (P<0.05).
CONCLUSIONCEA with butorphanol is safe and effective for the treatment of postoperative pain in elderly patients and causes less adverse effects than morphine.
