Advances in the study of bioactivity and structure-function relationship of regulatory peptide AcSDKP.
- Author:
Xiang HAN
1
;
De-Xin WANG
Author Information
1. Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China.
- Publication Type:Journal Article
- MeSH:
Animals;
Cell Proliferation;
drug effects;
Fibroblasts;
cytology;
Hematopoiesis;
drug effects;
Hematopoietic Stem Cells;
cytology;
Humans;
Molecular Structure;
Oligopeptides;
chemistry;
pharmacology;
Structure-Activity Relationship
- From:
Acta Pharmaceutica Sinica
2007;42(8):810-816
- CountryChina
- Language:Chinese
-
Abstract:
As a negative regulator of hematopoiesis, AcSDKP is well known to inhibit the proliferation of hematopoietic stem cells and reported to has a biological function in non-hematopoietic cells recently. Its biological activities and structure-function relationship are reviewed in this paper.
