Clinical analysis of transcatheter closure of atrial septal defects in dderly patients
10.3760/cma.j.issn.0253-3758.2011.11.005
- VernacularTitle:老年房间隔缺损患者介入治疗的临床分析
- Author:
Huo-Yuan CHEN
1
;
Xian-Yang ZHU
;
Xiu-Min HAN
;
Chuan-Ju HOU
;
Duan-Zhen ZHANG
;
Qi-Guang WANG
;
Xiao-Tang SHENG
;
Chun-Sheng CUI
Author Information
1. 沈阳军区总医院
- Keywords:
Heart septal defects,atrial;
Aged;
Heart catheterization
- From:
Chinese Journal of Cardiology
2011;39(11):993-996
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the clinical feature of patients with atrial septal defects (ASD)and the safety and efficacy of transcatheter closure of ASD in elderly patients.Methods Between May 2000and June 2010,82 patients aged (64.5 + 3.8)years underwent attempted transcatheter ASD closure.Right heart catheterization was performed before intervention.Echocardiography was made at 1 day,1,3,6 months after the procedure.The pre- and post-closure clinical feature,pulmonary artery pressure (PAP) and cardiac function were evaluated.Results In 82 patients,37 (45.1％) patients were associated with pulmonary arterial hypertension ( PAH ).The systolic PAP and mean PAP [ (44.1 ± 12.4) mm Hg ( 1mm Hg = 0.133 kPa) and (25.2 + 6.8) mm Hg,respectively ] were measured by right heart catheterization before the procedure.One patient was unsuitable for closure because of severe PAH.The remaining 81patients underwent successful ASD closure without major complications.After closuring,systolic PAP decreased from (52.7 ± 10.3 )mm Hg to (31.8 ± 6.3) mm Hg ( P ＜ 0.05 ),and mean PAP descended from (30.9 ± 4.7 ) mm Hg to (21.8 ± 3.4) mm Hg( P ＜ 0.05 ) in the 36 patients with PAH.The cardiac function improved post procedure.There were 6 new-onset atrial fibrillations during follow up.Conclusions ASD in elderly patients are commonly associated with PAH.Transcatheter ASD closure is safe and effective in the majority of elderly patients.
