Clinicopathologic analysis of myocardial infarction with or without left ventricular aneurysm formation in the elderly patients
10.3760/cma.j.issn.0253-3758.2011.11.010
- VernacularTitle:老年心肌梗死伴室壁瘤形成的临床病理特点分析
- Author:
Liu-Fa DUAN
1
;
YE-Ping
;
Yan-Song ZHENG
;
Li-Ping ZHANG
;
Fu-Lin WANG
Author Information
1. 解放军总医院
- Keywords:
Myocardial infarction;
Heart aneurysm;
Aged
- From:
Chinese Journal of Cardiology
2011;39(11):1021-1023
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the clinic-pathologic features of elderly myocardial infarction patients ( ＞ 60 years) with and without left ventricular aneurysm formation.Methods Between January 1980 and October 2009,107 myocardial infarction patients were divided into aneurysm group (n =31 ) and non-aneurysm group ( n = 76) according to autopsy results and the clinic-pathologic features of the two groups were compared.Results Previous angina pectoris history was significantly less in aneurysm group than in non-aneurysm group [ 45.2％ ( 14/31 ) vs.92.1％ ( 70/76 ),P = 0.047 ].Incidence of hypertension was significantly higher in aneurysm group than in non-aneurysm group [ 77.4％ (24/31) vs.36.8％ (28/76),P = 0.033 ].The percentage of single-vessel disease [54.8％ ( 17 /31 ) vs.23.7％(18/76),P =0.033] and the LAD disease [96.8％ (30/31) vs.51.3％ (39/76),P =0.048] were both significantly higher in aneurysm group than in non-aneurysm group.Heart failure and ventricular arrhythmias were more likely the cause of death in patients with aneurysm than patients without aneurysm [ 56.3％ (18/31) vs.19.7％ ( 15/76),P = 0.007 ].Aneurysm mostly located in left ventricular anterior wall and apex.Conclusions Our results suggest that patients with left ventricular aneurysm formation are more likely to have hypertension,single-vessel disease and LAD disease,heart failure and ventricular arrhythmias but less previous angina pectoris than patients without left ventricular aneurysm formation.The common locations of ventricular aneurvsm formation were left ventricular anterior wall and apex.
