Impact of obesity and hypertension on left atrium size
10.3760/cma.j.issn.0253-3758.2011.11.011
- VernacularTitle:肥胖和高血压与左心房增大关联度的比较研究
- Author:
Xi CHEN
1
;
Jin-Xiu LIN
Author Information
1. 福建医科大学附属第一医院
- Keywords:
Hypertension;
Obesity;
Heart atria
- From:
Chinese Journal of Cardiology
2011;39(11):1024-1028
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the impact of obesity and hypertension on the size of the left atrium.Methods A total of 383 subjects were divided into normal group (NS,n =95),hypertension group ( HT,n = 97 ),obesity group ( OB,n = 98 ) and hypertension with obesity group ( HT + OB,n = 93 ).Clinical information,echocardiographic parameters and left atrial size in the four groups were compared.Results ( 1 ) The left atrial volume index (LAVI) was arranged in the order:HT + OB ＞ OB ＞HT ＞ NS ( 28.07 + 6.63 ＞ 24.61 ± 4.89 ＞ 22.73 ± 5.16 ＞ 19.18 ± 4.82 ml/m,P ＜ 0.05 ) ; Difference on LAVI was significant in four groups after adjusting for age,gender,HR,FPG,TC,TG and HDL (P ＜0.05 ).(2) Pearson correlation analysis showed closer correlation between BMI with LAVI compared to SBP and DBP with LAVI (r values:0.505,0.240,0.209,P＜0.001).After adjusting for other factors,the correlation between BMI and LAVI remains significant ( β = 0.411,P ＜ 0.001 ) while no significant relationship between SBP,DBP and LAVI was found.One unit BMI increase is associated with 0.052 cmenlargement of left atrial diameter(LAD),1.053 ml increase of left atrial volume(LAY) and 0.710 ml/m increase of LAVI.Conclusion The impact of obesity on the size of left atrium is greater than that of hypertenstion.Obesity and hypertension have synergistic effects on enlarging left atria.
