A new eudesmane sesquiterpene lactone from Curcuma wenyujin.
- Author:
Shi-sheng WANG
1
;
Jin-mei ZHANG
;
Xiu-han GUO
;
Qi-ling SONG
;
Wei-jie ZHAO
Author Information
1. State Key Laboratory of Fine Chemical Engineering, Dalian University of Technology, Dalian 116012, China. wangssg@sina.com
- Publication Type:Journal Article
- MeSH:
Curcuma;
chemistry;
Molecular Structure;
Plants, Medicinal;
chemistry;
Rhizome;
chemistry;
Sesquiterpenes, Eudesmane;
chemistry;
isolation & purification
- From:
Acta Pharmaceutica Sinica
2007;42(10):1062-1065
- CountryChina
- Language:English
-
Abstract:
The aim of the study was to investigate the sesquiterpene constituents from the rhizomes of Curcuma wenyujin Y. H. Chen et C. Ling. The isolation and purification of the constituents from the 50% EtOH extracts of the rhizomes were performed with repeated column chromatography over sillica gel and macroporous resin. Eight sesquiterpenes were obtained and identified as wenyujinlactone A (1), neolitamone A (2), zedoarondiol (3), isozedoarondiol (4), aerugidiol (5), curcumol (6), curdione (7) and (1R, 10R)-epoxy-(-)-1, 10-dihydrocurdine (8) by means of spectral analysis. Among them, compound 1 was found to be a new eudesmane sesquiterpene lactone, whilst compounds 2-5 were obtained from this plant for the first time.
