Diterpenoids from bulbus of Fritillaria monanth.
- Author:
Hong-ning LIU
1
;
Fei LI
;
Yong-ming LUO
;
Wei-feng ZHU
;
Dong-mei YAN
;
Xing-fa HUANG
Author Information
1. Jiangxi University of Traditional Chinese Medicine, Nanchang 330006, China.
- Publication Type:Journal Article
- MeSH:
Diterpenes, Kaurane;
chemistry;
isolation & purification;
Fritillaria;
chemistry;
Molecular Structure;
Plant Roots;
chemistry;
Plants, Medicinal;
chemistry
- From:
Acta Pharmaceutica Sinica
2007;42(11):1152-1154
- CountryChina
- Language:Chinese
-
Abstract:
To study the chemical constituents of Fritillaria monanth Migo, the constituents were separated and purified by column chromatography on silica gel, and the structures were identified by NMR, MS spectral data. Six compounds were isolated and identified as ent-kauran-15-en-17-ol (I), entkauran-15-en-3alpha, 17-diol (II), fritillaziebinol (III), ent-kauran-16a, 17-diol (IV), ent-kauran-3alpha, 16alpha,17-triol (V), ent-16,17-epoxy-kauran-3alpha-ol (VI). All the compounds were isolated from this plant for the first time, and VI is named as ent-16,17-epoxy-kauran-3alpha-ol, which is a new compound.