Chemical constituents from the leaves of Broussonetia papyrifera.
- Author:
Wei-Sheng FENG
1
;
Hong-Wei LI
;
Xiao-Ke ZHENG
;
Hai-Xue KUANG
;
Sui-Qing CHEN
;
Yan-Zhi WANG
;
Xin-Yu ZANG
Author Information
1. Henan University of Traditional Chinese Medicine, School of Pharmacy, Zhengzhou 450008, China. fwsh@hactcm.edu.cn
- Publication Type:Journal Article
- MeSH:
Apigenin;
chemistry;
isolation & purification;
Broussonetia;
chemistry;
Glucosides;
chemistry;
isolation & purification;
Luteolin;
chemistry;
isolation & purification;
Molecular Structure;
Plant Leaves;
chemistry;
Plants, Medicinal;
chemistry
- From:
Acta Pharmaceutica Sinica
2008;43(2):173-180
- CountryChina
- Language:English
-
Abstract:
To separate and identify the chemical constituents from the leaves of Broussonetia papyrifera (Linn.) Vent, various columns including Diaion HP-20, Toyopearl HW-40C, Sephadex LH-20, silica gel were employed for the isolation and purification of compounds from the leaves of B. papyrifera. The structures of the compounds were elucidated by their physiochemical characteristics and spectral data. Nineteen compounds were isolated from the leaves of B. papyrifera and their structures were identified as apigenin (1), apigenin-7-O-beta-D-glucopyranoside (2), chrysoerid-7-O-beta-D-glucopyranoside (3), apigenin-7-O-beta-D-glucopyranuronide (4), vitexin-7-O-beta-D-glucopyranoside (5), luteolin (6), 5,7,4'-trihydroxyl-6-C-[a-L-rhamnopyranosyl (1-->2)]-beta-D-glucopyranosyl flavone (7), 5,7,4'-trihydroxyl-8-C-[a-L-rhamnopyranosyl (1-->2)]-beta-D-glucopyranosyl flavone (8), saponaretin (9), vitexin (10), benzyl benzoate-2, 6-di-O-beta-D-glucopyranoside (11), (2R, 3R, 5R, 6S, 9R)-3-hydroxy-5,6-epoxy-beta-ionol-2-O-beta-D-glucopyranoside (12), (2R, 3R, 5R, 6S, 9R)-3-hydroxyl-5,6-epoxy-acetyl-beta-ionol-2-O-beta-D-glucopyranoside (13), ficustriol (14), (6S, 9S)-roseoside (15), 3beta-hydroxy-5alpha,6alpha-epoxy-beta-ionone-2alpha-O-beta-D-glucopyranoside (16), icariside B1 (17), sammangaoside A (18), 3-hydroxy-5alpha,6alpha-epoxy-beta-ionone (19). Compounds 11, 12 and 13 are new compounds, the others are isolated from this genus Broussonetia for the first time.
