Detection of Helicobacter pylori in oral cavity of patients with recurrent aphthous ulcer.
- Author:
Bao-jun LONG
1
;
Ke CHEN
;
Bu-ling WU
;
Jian-min DUAN
Author Information
- Publication Type:Journal Article
- MeSH: Adult; Case-Control Studies; Female; Gastritis; microbiology; Helicobacter Infections; diagnosis; Helicobacter pylori; isolation & purification; Humans; Male; Mouth; microbiology; Peptic Ulcer; microbiology; Polymerase Chain Reaction; Recurrence; Saliva; microbiology; Stomatitis, Aphthous; microbiology
- From: Journal of Southern Medical University 2007;27(4):477-478
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo investigate the association of recurrent aphthous ulcer (RAU) with Helicobacter pylori (Hp) infection and digestive diseases.
METHODSSaliva samples were collected from 82 patients with RAU and 74 healthy volunteers for Hp detection with PCR.
RESULTSThe positivity rates of HP differed significantly between RAU patients and healthy volunteers (43.9% vs 16.2%, P<0.001). In the 82 RAU patients, 22 (26.82%) were identified to have gastritis and peptic ulcer, whereas only 7 out of the 74 healthy volunteers (10.45%) had such digestive diseases, showing significant difference between them (P<0.01).
CONCLUSIONHp might in some way associate with RAU, which in turn is associated with an increased incidence of digestive diseases.
