Expression of aquaporins 1, 3, 8, 9 mRNA in human fetal membranes.
- Author:
Rui ZHANG
1
;
Dong-Zi YANG
;
Ying-Lin LIU
;
Chen-Yu GOU
;
Jian-Ping ZHANG
;
Yun-Hui WANG
Author Information
- Publication Type:Journal Article
- MeSH: Adult; Amnion; embryology; metabolism; Aquaporin 1; genetics; Aquaporin 3; genetics; Aquaporins; genetics; Chorion; embryology; metabolism; Electrophoresis, Agar Gel; Extraembryonic Membranes; embryology; metabolism; Female; Gene Expression Regulation, Developmental; Humans; Pregnancy; Reverse Transcriptase Polymerase Chain Reaction
- From: Journal of Southern Medical University 2007;27(5):702-704
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo investigate the expression of aquaporin (AQP)-1, 3, 8, 9 in human fetal membrane and their role in the human amniotic fluid circulation.
METHODSRT-PCR was employed for detection of the expressions of AQP-1, 3, 8, 9 mRNA in human amnion and chorion from 20 women with normal term pregnancy.
RESULTSAQP-1, 3, 8, 9 mRNA expression was detected in both human amnion and chorion, and no significant difference was found in their expression levels or between the amnion and chorion (P>0.05).
CONCLUSIONAQP-1, 3, 8, 9 can be associated with intramembranous transport and volume regulation of amniotic fluid.
