The value of histopathologic examination of testis tissue from testicular sperm aspiration.
- Author:
Shen-Min YANG
1
;
Bing CHEN
;
Yi-Chao SHI
;
Duan-Gai WEN
;
Hong LI
;
Wei WANG
;
Hong-Bo CHENG
Author Information
- Publication Type:Journal Article
- MeSH: Adult; Azoospermia; pathology; Humans; Male; Middle Aged; Sperm Count; Sperm Retrieval; Testis; pathology; Young Adult
- From: National Journal of Andrology 2013;19(10):899-901
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo evaluate histopathologic examination of the testis tissue from testicular sperm aspiration (TESA).
METHODSWe analyzed the results of inverted microscopy and histopathologic examination of 96 samples of testis tissue from TESA, and compared the accuracy of the two methods in detecting sperm in the testis tissue.
RESULTSAmong the 11 cases in which sperm was found by inverted microscopy, 9 were confirmed by histopathologic examination, and among the 57 cases in which sperm was not detected by inverted microscopy, 11 (19.3%) were found with sperm by histopathologic examination. Histopathologically, the cases in which sperm was not found by inverted microscopy included Sertoli-cell-only syndrome (n = 34), maturation arrest (n = 12) and hypospermatogenesis (n = 11).
CONCLUSIONHistopathologic examination may reveal sperm in the TESA testis tissue proved to be sperm-absent by microscopy, and thus offer valuable information for a second testicular sperm retrieval.