Histological classification of lymph node malignant non-Hodgkin lymphoma based on the new WHO 2001 classification.
- Author:
Huong Duc Tran
;
Roanh Dinh Le
;
Hoe Duc Le
;
Chu Van Nguyen
- Publication Type:Journal Article
- Keywords:
Malignant non Hodgkin lymphoma;
new WHO 2001 classification;
treatment
- MeSH:
Lymphoma;
Non-Hodgkin/ pathology;
epidemiology Neoplasms by Histologic Type
- From:Journal of Medical Research
2007;47(2):38-44
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
Background: Non-Hodgkin's lymphoma is a malignant (cancerous) growth of B or T white blood cells (lymphocytes) in the lymph system. Many lymphoma classifications were proposed. All were based by groups of the original cells, histopathological appearances and clinical features. Purpose: Histological classification of lymph node malignant non - \r\n", u'Hodgkin lymphoma based on the new WHO 2001 classification. Objectives: To apply new WHO 2001 classification of 165 cases of malignant non Hodgkin lymphoma were histopathologically and immunohisto chemically studied at K hospital in Hanoi. Subjects and method: The study included 165 patients with malignant non Hodgkin lymphoma were examined and treated at K hospital in Hanoi from 2000 to 2003. Results: The study based on new WHO 2001 classification of 165 cases of malignant non Hodgkin lymphoma showed results B lymphoma: Diffuse large B - cell lymphoma accounts for 63.3%, follicular lymphoma: 17.5%, small lymphocytic lymphoma: 12.5%, mantle cell lymphoma: 1.7% and the others are at low rate. T lymphoma: large T-cell lymphoma accounts for 35.0%, T lymphoblastic lymphoma: 30.0%, angioimmunoblastic T-cell lymphoma: 12.5%, peripheral T- cell lymphoma, unspecified: 10.0%, the others are at low rate. Conclusion: We concluded that new WHO classification of malignant non Hodgkin is reproducible in our practice and should be useful in the treatment decision. \r\n', u'