LncRNA in prostate cancer: an update.
- Author:
Xiu-Quan GUO
1
;
Tian LAN
2
;
Yang-Min WANG
2
Author Information
1. Department of Urology, The Second School of Clinical Medicine, Lanzhou University/Lanzhou General Hospital of Lanzhou Military Region, Lanzhou, Gansu 730050, China. guoxiuquan846@163.com
2. Department of Urology, The Second School of Clinical Medicine, Lanzhou University/Lanzhou General Hospital of Lanzhou Military Region, Lanzhou, Gansu 730050, China.
- Publication Type:Journal Article
- MeSH:
Biomarkers, Tumor;
Humans;
Male;
Prostatic Neoplasms;
genetics;
RNA, Long Noncoding
- From:
National Journal of Andrology
2013;19(9):826-830
- CountryChina
- Language:Chinese
-
Abstract:
Recent studies have demonstrated the importance of the non-protein coding part of human genome in carcinogenesis and metastasis of prostate cancer. Long non-coding RNAs (lncRNAs) play a key regulatory role in prostate cancer biology. LncRNAs are dysregulated in prostate cancer and the expression levels of certain lncRNAs are associated with the recurrence, metastasis and prognosis of cancer. It is also proved that lncRNAs, as oncogenes, can promote carcinogenesis and development of prostate cancer. This review focuses on the progress in the studies of lncRNAs in prostate cancer.
